Autonomic dysfunction in parkinsonian disorders: assessment and pathophysiology

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Autonomic dysfunction in parkinsonian disorders: assessment and pathophysiology.

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by motor dysfunction (parkinsonism) and several non-motor features. Dysautonomia is a significant non-motor feature as well as a neuropsychiatric symptom. Autonomic dysfunction can occur even in the early stages of PD, often preceding the onset of the classic motor symptoms of PD. The patterns of autonomic featur...

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Autonomic Dysfunctions in Parkinsonian Disorders

BACKGROUND AND PURPOSE Symptoms of autonomic dysfunctions are common in the patients with parkinsonian disorders. Because clinical features of autonomic dysfunctions are diverse, the comprehensive evaluation is essential for the appropriate management. For the appreciation of autonomic dysfunctions and the identification of differences, patients with degenerative parkinsonisms are evaluated usi...

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Cardiovascular Autonomic Dysfunction in Parkinsonian Syndromes

Autonomic nervous system (ANS) disturbances are common in Parkinson's disease (PD), but also in other Parkinsonian syndromes, especially in multiple system atrophy (MSA). The differentiation between various Parkinsonian syndromes may be difficult, but it is important for prognostic and therapeutic purposes. The aim of this study was to determine the ability of different analysis methods to reve...

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Cardiovascular dysfunction in parkinsonian disorders.

Parkinsonian disorders comprise a variety of diseases, with differing pathology, natural history and prognosis. Although the most common is idiopathic (classical) Parkinson’s disease (PD), there is increasing recognition of ‘atypical’ parkinsonian disorders, such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP) and Lewy body disease (LBD) (1) (Fig. 1, see over). In some pa...

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Parkinsonian Disorders and Pure Autonomic Failure

INTRODUCTION Disorders of bladder, bowel and sexual function are common problems in Parkinson’s disease (PD), multiple system atrophy (MSA) and pure autonomic failure (PAF). Although the pathology of PD and MSA is quite different and distinct, the differential diagnosis of the conditions in life, particularly in the early stages, may be difficult and the presence of autonomic failure, as indica...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 2012

ISSN: 0022-3050

DOI: 10.1136/jnnp-2012-303135